SCHEMBL9079768

SCHEMBL9079768

CC(C[Si](Cl)(Cl)CC[Si](C)(Cl)Cl)c1ccccc1F

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
MAPKAPK2 P49137 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5488485 0.80 CYP3A4 (0.41) CYP3A4MAPKAPK2
SCHEMBL9080403 0.77 AOC3 (0.43)
SCHEMBL9079772 0.74 DAO (0.33)
SCHEMBL9078907 0.73 ESR1 (0.33)
SCHEMBL9079972 0.73 ESR1 (0.33)
SCHEMBL20228717 0.71 CYP3A4 (0.38) CYP3A4
SCHEMBL9080668 0.71
SCHEMBL9078908 0.71
SCHEMBL9080820 0.69 ESR1 (0.32)
SCHEMBL778759 0.68 TSHR (0.59) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527934-A HYDROSILATING BIS(DICHLOROSILYL)METHANES WITH ORGANOOLEFINS OR ORGANOSILYLOLEFINS IN THE PRESENCE OF CHLOROPLATINIC ACID CATALYST KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1996-06-18 US disclosed