Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079768 | 0.80 | CYP3A4 (0.33) | CYP3A4MAPKAPK2 | |
| SCHEMBL5486163 | 0.78 | ADRB2 (0.43) | CYP3A4TSHRIDO1TDO2CYP2C9 | |
| SCHEMBL7614292 | 0.78 | ESR1 (0.42) | CYP3A4TSHRCYP2C9SLC6A2SLC6A4 | |
| SCHEMBL5494557 | 0.77 | HTT (0.42) | CYP3A4TSHRIDO1TDO2CYP2C9 | |
| SCHEMBL11839515 | 0.76 | TSHR (0.33) | TSHRKMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL5488086 | 0.76 | TSHR (0.37) | CYP3A4TSHRALDH1A1MAPTSLC6A2 | |
| SCHEMBL18488721 | 0.75 | CYP3A4 (0.41) | CYP3A4TSHRIDO1TDO2MEN1 | |
| SCHEMBL20807370 | 0.75 | TSHR (0.59) | CYP3A4TSHRIDO1TDO2MEN1 | |
| SCHEMBL21138699 | 0.75 | TSHR (0.59) | CYP3A4TSHRIDO1TDO2MEN1 | |
| SCHEMBL778759 | 0.75 | TSHR (0.59) | CYP3A4TSHRIDO1TDO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |