Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079247 | 0.91 | NR4A2 (0.39) | GABRA1GABRB2KDM4EKCNH2LMNA | |
| SCHEMBL9078734 | 0.88 | LMNA (0.37) | KDM4ELMNAAHRMAPTKCNK3 | |
| SCHEMBL9077618 | 0.87 | AHR (0.37) | GABRA1GABRB2KDM4EAHRMAPT | |
| SCHEMBL9277713 | 0.86 | NR4A2 (0.38) | GABRA1GABRB2KDM4EKCNH2LMNA | |
| SCHEMBL9077919 | 0.80 | AHR (0.34) | GABRA1GABRB2KDM4EKCNH2AHR | |
| SCHEMBL9078562 | 0.80 | KDM4E (0.35) | KDM4ELMNAHSD17B10MAPTPLA2G1B | |
| SCHEMBL9079761 | 0.80 | AHR (0.34) | GABRA1GABRB2KDM4EAHRMAPT | |
| SCHEMBL9080914 | 0.78 | KDM4E (0.39) | KDM4ELMNAHPGDMAPTKMT2A | |
| SCHEMBL9281297 | 0.74 | MCL1 (0.40) | KDM4ELMNAHPGDHSD17B10KMT2A | |
| SCHEMBL9278661 | 0.72 | MCL1 (0.37) | KDM4ELMNAHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512590-A | PREVENTS DISORDER OF GABAERGIC TRANSMISSION | SYNTHELABO (FR) | 1996-04-30 | — | — | US | disclosed |
| EP-0682025-A1 | 5,6-dihydro-4H-imidazo 2',1':2,3 imidazo 4,5,1-ij quinoline and 4,5-dihydroimidazo 1,2-a pyrrolo 1,2,3-cd benzimidazol derivatives | SYNTHELABO (FR) | 1995-11-15 | — | — | EP | disclosed |