Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875468 | 0.93 | HINT1 (0.50) | HINT1POLBF2GSK3ARPS6KA3 | |
| SCHEMBL8447610 | 0.93 | HINT1 (0.50) | HINT1POLBF2GSK3ARPS6KA3 | |
| SCHEMBL5355041 | 0.93 | HINT1 (0.50) | HINT1POLBF2GSK3ARPS6KA3 | |
| SCHEMBL5352518 | 0.93 | HINT1 (0.50) | HINT1POLBF2GSK3ARPS6KA3 | |
| SCHEMBL5182230 | 0.92 | POLB (0.51) | HINT1POLBF2GSK3ARPS6KA3 | |
| SCHEMBL5347882 | 0.90 | POLB (0.63) | HINT1POLBF2GSK3ARPS6KA3 | |
| SCHEMBL23352540 | 0.87 | POLB (0.54) | HINT1POLBGSK3ARPS6KA3MAPK14 | |
| SCHEMBL17001491 | 0.87 | POLB (0.54) | HINT1POLBGSK3ARPS6KA3MAPK14 | |
| SCHEMBL3893075 | 0.87 | POLB (0.54) | HINT1POLBGSK3ARPS6KA3MAPK14 | |
| SCHEMBL18769456 | 0.87 | POLB (0.54) | HINT1POLBGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355131-B1 | ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF | PRO NEURON INC (US) | 1996-09-04 | — | — | EP | disclosed |