Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081676 | 0.89 | MAPT (0.58) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| Iodide SCHEMBL9082436 | 0.87 | HTR2B (0.60) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL9082855 | 0.81 | HTR2B (0.58) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| Iodide SCHEMBL9081392 | 0.81 | HTR2B (0.57) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL9080615 | 0.80 | HTR2B (0.62) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL9081671 | 0.79 | MAPT (0.61) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| Iodide SCHEMBL9080930 | 0.78 | HTR2B (0.57) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL1148605 | 0.78 | HTR2B (0.62) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL29757934 | 0.78 | HTR2B (0.58) | HTR2BMEN1KMT2ATP53CYP1A2 | |
| SCHEMBL13808316 | 0.78 | HTR2B (0.58) | HTR2BMEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039382-A1 | UREA DERIVATIVES AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-12 | — | — | WO | disclosed |