Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901088 | 0.91 | NPC1 (0.43) | NPC1GAACA1CA2CA5A | |
| Sulfometuron Methyl SCHEMBL9137833 | 0.90 | GAA (0.50) | NPC1GAACA1CA2CA5A | |
| Sulfometuron Methyl SCHEMBL54998 | 0.90 | GAA (0.50) | NPC1GAACA1CA2CA5A | |
| Sulfometuron Methyl SCHEMBL27545620 | 0.90 | GAA (0.50) | NPC1GAACA1CA2CA5A | |
| SCHEMBL10566429 | 0.89 | LMNA (0.43) | NPC1GAACA1CA2CA9 | |
| Sulfometuron Methyl SCHEMBL15524982 | 0.89 | GAA (0.49) | NPC1GAACA1CA2CA5A | |
| Sulfometuron Methyl SCHEMBL2438199 | 0.86 | NPC1 (0.49) | NPC1GAACA1CA2CA5A | |
| SCHEMBL9419172 | 0.85 | GAA (0.52) | NPC1GAACA1CA2CA5A | |
| SCHEMBL9079811 | 0.84 | NPC1 (0.47) | NPC1GAACA1CA2CA5A | |
| SCHEMBL10455401 | 0.82 | GAA (0.43) | NPC1GAACA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554240-B1 | EXPRESSION OF HERBICIDE METABOLIZING CYTOCHROMES P450 | DU PONT (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5349127-A | Expression of herbicide metabolizing cytochromes P450 | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0554240-A1 | EXPRESSION OF HERBICIDE METABOLIZING CYTOCHROMES P450. | DU PONT (US) | 1993-08-11 | — | — | EP | disclosed |
| US-5212296-A | DNA sequences | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| WO-1991003561-A1 | EXPRESSION OF HERBICIDE METABOLIZING CYTOCHROMES P450 | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-21 | — | — | WO | disclosed |