Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 4/20 | 0.47 |
| ▸ | MC5R | P33032 | 4/20 | 0.47 |
| ▸ | MC1R | Q01726 | 4/20 | 0.47 |
| ▸ | MC3R | P41968 | 3/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081031 | 0.87 | TSHR (0.53) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9080371 | 0.86 | TSHR (0.55) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9081721 | 0.86 | TSHR (0.55) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9080531 | 0.86 | TSHR (0.55) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9081215 | 0.86 | TSHR (0.55) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9082575 | 0.85 | LPAR1 (0.56) | LPAR1LPAR5 | |
| SCHEMBL9081637 | 0.84 | LPAR1 (0.54) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9080541 | 0.83 | TSHR (0.53) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9080843 | 0.83 | TSHR (0.53) | LPAR1LPAR5STAT3TSHRTDP1 | |
| SCHEMBL9081773 | 0.82 | LPAR1 (0.53) | LPAR1LPAR5TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |