SCHEMBL9080388

SCHEMBL9080388

O=c1c(O)c(-c2ccco2)oc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.62
KMT2A Q03164 11/20 0.62
KDM4E B2RXH2 11/20 0.62
CYP3A4 P08684 7/20 0.62
MAPK1 P28482 5/20 0.62
TP53 P04637 5/20 0.62
ALOX15 P16050 3/20 0.62
PKM P14618 2/20 0.62
LMNA P02545 2/20 0.62
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
ABCB1 P08183 1/20 0.62
CALM1 P0DP23 1/20 0.62
AR P10275 1/20 0.62
CYP1B1 Q16678 1/20 0.62
CA9 Q16790 1/20 0.62
ALDH1A1 P00352 8/20 0.61
HTT P42858 4/20 0.61
HSD17B10 Q99714 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399371 1.00 MEN1 (0.62) MEN1KMT2AKDM4ECYP3A4MAPK1
Acrylic Acid SCHEMBL29740694 0.89 KDM4E (0.56) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL17786390 0.81 MAPT (0.51) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL27380285 0.81 ALDH1A1 (0.61) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL31723132 0.81 ALDH1A1 (0.62) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL20918463 0.81 ALDH1A1 (0.62) MEN1KMT2AKDM4ECYP3A4MAPK1
Flavonol SCHEMBL31328341 0.79 KDM4E (0.97) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL11636258 0.79 ALDH1A1 (0.66) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL9659870 0.79 KMT2A (0.62) MEN1KMT2AKDM4ECYP3A4MAPK1
SCHEMBL2746872 0.78 MEN1 (0.90) MEN1KMT2AKDM4ECYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043688-A1 STABILIZED SILOXANE PARTICLES AND METHODS FOR MAKING AND USING THE SAME FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-02-08 US disclosed
US-5552551-A COLORS FOR PHOSPHORESCENCE FLORIDA STATE UNIVERSITY (US) 1996-09-03 US disclosed
WO-1995003343-A1 PROTON-TRANSFER, LOW SELF-ABSORBING CHROMOPHORES FOR USE IN SCINTILLATORS FLORIDA STATE UNIVERSITY (US) 1995-02-02 WO disclosed