Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237730 | 0.81 | POLB (0.43) | POLBELANEALDH1A1CHRM2CHRM1 | |
| SCHEMBL3681001 | 0.77 | POLB (0.45) | POLBELANECHRM2CHRM1CHRM4 | |
| SCHEMBL23641912 | 0.74 | LMNA (0.39) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL23641774 | 0.74 | LMNA (0.39) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL24750156 | 0.69 | POLB (0.38) | POLBELANECHRM2CHRM1CHRM4 | |
| SCHEMBL25090572 | 0.68 | POLB (0.42) | POLBCHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL6095759 | 0.68 | POLB (0.42) | POLBALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1333553 | 0.68 | POLB (0.42) | POLBALDH1A1 | |
| SCHEMBL7893349 | 0.68 | POLB (0.42) | POLBALDH1A1 | |
| SCHEMBL52102 | 0.68 | POLB (0.42) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571909-A | ANTIBIOTICS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-11-05 | — | — | US | disclosed |