Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081356 | 0.92 | KDM4E (1.00) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9081633 | 0.88 | ALDH1A1 (0.66) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9080543 | 0.83 | KDM4E (0.77) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL5947412 | 0.81 | KDM4E (0.79) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9080552 | 0.80 | ALDH1A1 (0.76) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL13973181 | 0.78 | ALDH1A1 (0.58) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9081613 | 0.77 | MEN1 (0.65) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27099852 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL6511911 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15474270 | 0.76 | MAOB (0.52) | KDM4EALDH1A1MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |