Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080695 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL10445714 | 0.88 | TDP1 (0.54) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL10424136 | 0.88 | TDP1 (0.54) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| Malonic Acid SCHEMBL9222810 | 0.86 | TDP1 (0.48) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL6685471 | 0.86 | RAB9A (0.47) | ALDH1A1LMNACYP3A4HSD17B10L3MBTL1 | |
| SCHEMBL33928 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL1331551 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL33927 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL1531678 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1LMNATSHRCYP3A4 | |
| SCHEMBL1330911 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1LMNATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701568-A1 | NEW PEPTIDE DERIVATIVES | Astra Aktiebolag (SE) | 1996-03-20 | — | — | EP | disclosed |