Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 6/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038869 | 0.98 | GSTP1 (0.56) | GSTP1PPARAPPARGLTA4HPTGS2 | |
| Ammonia Solution, Strong SCHEMBL27628949 | 0.82 | DPP4 (0.58) | PPARAPPARGPTGS2DPP4TRPA1 | |
| SCHEMBL13675365 | 0.81 | ABL1 (0.56) | PPARAPPARGFFAR4FFAR1TSHR | |
| SCHEMBL9618332 | 0.81 | DPP4 (0.56) | PPARAPPARGPTGS2LMNAHTT | |
| SCHEMBL328862 | 0.80 | DPP4 (0.60) | PPARAPPARGPTGS2DPP4TRPA1 | |
| SCHEMBL31261742 | 0.80 | DPP4 (0.60) | PPARAPPARGPTGS2DPP4TRPA1 | |
| SCHEMBL2498575 | 0.80 | GSTP1 (0.52) | GSTP1PPARAPPARGLTA4HPTGS2 | |
| SCHEMBL5833074 | 0.80 | FFAR1 (0.58) | PPARAPPARGLTA4HFFAR4FFAR1 | |
| Ethane SCHEMBL3681665 | 0.78 | DPP4 (0.58) | PPARAPPARGPTGS2DPP4TRPA1 | |
| Water SCHEMBL9719797 | 0.78 | DPP4 (0.58) | PPARAPPARGPTGS2DPP4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |