SCHEMBL13675365

SCHEMBL13675365

CCc1ccccc1-c1ccc(OC)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.56
ABCB1 P08183 1/20 0.56
BCR P11274 1/20 0.56
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52
FFAR1 O14842 1/20 0.52
FFAR4 Q5NUL3 1/20 0.52
MAPT P10636 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
HPGD P15428 1/20 0.51
ATM Q13315 1/20 0.51
HTR7 P34969 1/20 0.49
PTPN1 P18031 1/20 0.49
GFER P55789 1/20 0.48
IDO1 P14902 1/20 0.47
NPC1 O15118 2/20 0.47
TP53 P04637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4375331 0.85 PPARA (0.53) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL1520607 0.85 ABL1 (0.56) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL13366126 0.84 CD274 (0.47) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL13699903 0.84 ABL1 (0.47) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL10821571 0.83 ABL1 (0.55) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL9290083 0.83 ABL1 (0.59) ABL1ABCB1BCRPPARGPPARA
SCHEMBL3756401 0.83 DPP4 (0.62) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL29038869 0.83 GSTP1 (0.56) PPARGPPARAFFAR1FFAR4TSHR
SCHEMBL8529161 0.83 ABL1 (0.55) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL28792762 0.83 ABL1 (0.55) ABL1ABCB1BCRHDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114622226-B Method for electrocatalytic synthesis of alkyl borate 中国科学院大连化学物理研究所 2023-09-08 CN disclosed
CN-114345370-B Method for reduction cross coupling of photocatalytic aromatic olefin and halogenated hydrocarbon 陕西师范大学 2023-07-21 CN disclosed
CN-114622226-A Method for synthesizing alkyl borate through electrocatalysis 中国科学院大连化学物理研究所 2022-06-14 CN disclosed
CN-104918961-A Improved peptide drugs for insulin resistance MEDERIS DIABETES LLC 2015-09-16 CN disclosed
US-20090270381-A1 Non-steroidal progesterone receptor modulators BAYER SCHERING PHARMA AG (DE) 2009-10-29 US disclosed
WO-2009077186-A1 NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESLLSCHAFT (DE) 2009-06-25 WO disclosed
US-20090075989-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AG (DE) 2009-03-19 US disclosed
WO-2008077646-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270381-A1 Non-steroidal progesterone receptor modulators PGR, PGRMC1, PGRMC2 ABL1 4456/4885ABCB1 963/4885BCR 3226/4885
US-20090075989-A1 NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS NR5A1, CYP19A1, GPER1 ABL1 4467/4885ABCB1 903/4885BCR 3371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.