Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607175 | 0.84 | HTT (0.67) | ALDH1A1HTTMEN1KMT2ACHRM2 | |
| SCHEMBL8497858 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL7756966 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9080546 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9080543 | 0.81 | KDM4E (0.77) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9079843 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL8493646 | 0.80 | HTT (0.82) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL9079986 | 0.79 | MAPK1 (0.70) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| Diphenylether SCHEMBL11163283 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL40401 | 0.78 | CHRM2 (0.69) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |