Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312115 | 0.88 | MAPK1 (0.77) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30877044 | 0.88 | MAPK1 (0.77) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9080552 | 0.88 | ALDH1A1 (0.76) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9080546 | 0.86 | KDM4E (0.61) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9080058 | 0.85 | LTA4H (0.55) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9080543 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL27313687 | 0.85 | MAPK1 (0.78) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9081633 | 0.83 | ALDH1A1 (0.66) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9081570 | 0.83 | KDM4E (0.52) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9033719 | 0.83 | MAPK1 (0.73) | MAPK1KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |