Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SHBG | P04278 | 3/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13125426 | 1.00 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL907789 | 1.00 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL14535132 | 1.00 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10599486 | 1.00 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL12902155 | 1.00 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL6843517 | 0.86 | CYP19A1 (0.65) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL14946858 | 0.86 | CYP19A1 (0.65) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL908750 | 0.85 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL12902157 | 0.85 | CYP19A1 (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL10599356 | 0.83 | CYP19A1 (0.61) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215104-B1 | 11 -FLUORO-3-ACETOXYESTRA-3,5-DIENE-17-ON AND METHOD FOR THE PRODUCTION THEREOF | BAYER IP GMBH (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20110009654-A1 | 11B-FLUORO-3-ACETOXYESTRA-3,5-DIEN-17-ONE AND METHOD FOR THE PRODUCTION THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-01-13 | — | — | US | disclosed |
| US-7667056-B2 | Desogestrel synthesis characterized by regioselective reduction of a diketo intermediate 18-methyl-11-hydroxyestr-4-en-3,17-dione; higher yields, easier purification | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 2010-02-23 | — | — | US | disclosed |
| US-7667056-B2 | Desogestrel synthesis characterized by regioselective reduction of a diketo intermediate 18-methyl-11-hydroxyestr-4-en-3,17-dione; higher yields, easier purification | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 2010-02-23 | — | — | US | disclosed |
| EP-2053055-A1 | 11.beta.-fluoro-3-acetoxyestra-3,5-diene-17-one and method for its manufacture | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-04-29 | — | — | EP | disclosed |
| US-7361645-B2 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AG (DE) | 2008-04-22 | — | — | US | disclosed |
| EP-1353938-B1 | ANDROGENIC 7-SUBSTITUTED 11-HALOGENATED STEROIDS | BAYER SCHERING PHARMA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-04-07 | — | — | US | disclosed |
| US-6677324-B1 | MIXTURE INCLUDES 7A-(E-AMINOALKYL)-ESTRATRIENE; HORMONE REPLACEMENT THERAPY; MENOPAUSE | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-13 | — | — | US | disclosed |
| US-20030069434-A1 | 11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES, METOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11BETA-HALOGEN-7ALPHA- SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075322-A1 | Androgenic 7-substituted 11-halogen steroids | NR5A1, HSD17B11, HSD11B1 | CYP19A1 14/4885SERPINA6 188/4885ALDH1A1 855/4885 |
| US-20110009654-A1 | 11B-FLUORO-3-ACETOXYESTRA-3,5-DIEN-17-ONE AND METHOD FOR THE PRODUCTION THEREOF | HSD17B11, CYP19A1, HSD11B1 | CYP19A1 2/4885SERPINA6 2471/4885ALDH1A1 133/4885 |
| US-20030069434-A1 | 11BETA-HALOGEN-7ALPHA-SUBSTITUTED ESTRATRIENES, METOD FOR PRODUCING PHARMACEUTICAL PREPARATIONS CONTAINING SAID 11BETA-HALOGEN-7ALPHA- SUBSTITUTED ESTRATRIENES AND USE OF THE SAME FOR PRODUCING MEDICAMENTS | CYP19A1, HSD17B11, NR5A1 | CYP19A1 1/4885SERPINA6 645/4885ALDH1A1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.