Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CDK14 | O94921 | 2/20 | 0.41 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082430 | 0.84 | KMT2A (0.45) | SMN1; SMN2KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9232325 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1MAPTCDK5 | |
| SCHEMBL9080622 | 0.84 | KMT2A (0.46) | SMN1; SMN2KMT2ARAB9AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL9082566 | 0.82 | KMT2A (0.45) | SMN1; SMN2KMT2ARAB9AMEN1POLB | |
| Hydrochloric Acid SCHEMBL9080969 | 0.82 | KMT2A (0.49) | TSHRKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9081462 | 0.81 | KMT2A (0.48) | SMN1; SMN2KMT2ARAB9AMEN1POLB | |
| SCHEMBL9081290 | 0.81 | TSPO (0.47) | SMN1; SMN2KMT2AMEN1TDP1POLB | |
| Hydrochloric Acid SCHEMBL9081518 | 0.81 | HDAC2 (0.49) | SMN1; SMN2KMT2AMEN1CRHBPHTT | |
| SCHEMBL9228353 | 0.80 | KMT2A (0.43) | SMN1; SMN2KMT2ARAB9AMEN1POLB | |
| Hydrochloric Acid SCHEMBL9080145 | 0.80 | MEN1 (0.43) | SMN1; SMN2KMT2AMEN1POLBCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034866-A1 | IMIDAZO 1,2-A PYRIDINE AND IMIDAZO 1,2-A PYRIDEZINE DERIVATIVES AND THEIR USE AS BONE RESORPTION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |