Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | TYR | P14679 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312488 | 0.86 | CA2 (0.64) | CA12CA1CA2CA9TYR | |
| SCHEMBL71224 | 0.85 | CA12 (0.84) | CA12CA1CA2CA9TYR | |
| SCHEMBL5057418 | 0.85 | CA12 (0.84) | CA12CA1CA2CA9TYR | |
| SCHEMBL28435747 | 0.85 | CA2 (0.62) | CA12CA1CA2CA9TYR | |
| SCHEMBL28041658 | 0.85 | CA2 (0.62) | CA12CA1CA2CA9TYR | |
| SCHEMBL28207122 | 0.85 | CA2 (0.62) | CA12CA1CA2CA9TYR | |
| SCHEMBL19122351 | 0.85 | CA2 (0.62) | CA12CA1CA2CA9TYR | |
| SCHEMBL5216422 | 0.82 | CA12 (0.67) | CA12CA1CA2CA9CA7 | |
| SCHEMBL5216407 | 0.82 | CA12 (0.67) | CA12CA1CA2CA9CA7 | |
| SCHEMBL11700837 | 0.82 | MAOB (0.63) | CA2TYRMAOBPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040982-A1 | THERAPEUTIC INHIBITION OF PHOSPHOLIPASE A2 IN NEURODEGENERATIVE DISEASE | ATHENA NEUROSCIENCES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |