Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292485 | 0.84 | TSHR (0.49) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL9292668 | 0.84 | ALDH1A1 (0.42) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL9600220 | 0.80 | KMT2A (0.42) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL19458000 | 0.74 | GSK3B (0.46) | POLBALDH1A1MAPTRAB9ATDP1 | |
| SCHEMBL10061717 | 0.74 | MAPT (0.50) | POLBALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL9292488 | 0.73 | POLB (0.39) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL27489609 | 0.73 | NPSR1 (0.42) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL9085793 | 0.72 | ALDH1A1 (0.49) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL9292903 | 0.72 | HTT (0.41) | POLBALDH1A1MAPTRAB9AHTT | |
| SCHEMBL9293334 | 0.71 | KMT2A (0.42) | POLBALDH1A1HTTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512588-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-30 | — | — | US | disclosed |
| WO-1995018126-A1 | FURYLTHIAZOLE AND THEIR USE AS H2-RECEPTOR ANTAGONISM AND ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |
| CN-1097010-A | Novel furyl thiazole derivatives and salts thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-04 | — | — | CN | disclosed |
| EP-0355612-B1 | Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0598906-A1 | FURYLTHIAZOLE AND THEIR USE AS H 2?-RECEPTOR ANTAGONISM AND ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5308857-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| WO-1994003450-A1 | FURYLTHIAZOLE AND THEIR USE AS H2-RECEPTOR ANTAGONISTS AND ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-17 | — | — | WO | disclosed |
| WO-1993003028-A1 | FURYLTHIAZOLE AND THEIR USE AS H2-RECEPTOR ANTAGONISM AND ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |
| EP-0355612-A2 | Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |