SCHEMBL9083115

SCHEMBL9083115

CC(C)(c1ccccc1)c1ccccc1OP(=O)(O)Oc1ccccc1C(C)(C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.41
ALDH1A1 P00352 4/20 0.39
PTPN1 P18031 1/20 0.39
ESR1 P03372 1/20 0.39
CYP3A4 P08684 1/20 0.39
ESR2 Q92731 1/20 0.39
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
HPGD P15428 1/20 0.38
PDE3A Q14432 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 1/20 0.38
SRC P12931 3/20 0.36
ALOX15 P16050 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
PTPN5 P54829 1/20 0.35
MAPK1 P28482 1/20 0.34
INPPL1 O15357 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5077473 0.90 ALDH1A1 (0.49) ALDH1A1PTPN1ESR1CYP3A4ESR2
SCHEMBL2142942 0.86 ALDH1A1 (0.37) ALDH1A1PTPN1ESR1CYP3A4ESR2
Boric Acid SCHEMBL28327883 0.84 SRC (0.44) ALDH1A1PTPN1ESR1CYP3A4ESR2
SCHEMBL11508052 0.83 ALDH1A1 (0.35) ALDH1A1PTPN1ESR1CYP3A4ESR2
SCHEMBL2138387 0.83 ALDH1A1 (0.41) GPR84ALDH1A1PTPN1ESR1CYP3A4
SCHEMBL818786 0.82 TDP1 (0.46) GPR84ALDH1A1KDM4EHSD17B10SRC
SCHEMBL29462669 0.82 TDP1 (0.46) GPR84ALDH1A1KDM4EHSD17B10SRC
SCHEMBL5374705 0.81 CYP3A4 (0.38) ALDH1A1ESR1CYP3A4ESR2KDM4E
SCHEMBL1548706 0.81 CYP3A4 (0.38) ALDH1A1ESR1CYP3A4ESR2KDM4E
SCHEMBL11506209 0.81 ALDH1A1 (0.38) ALDH1A1ESR1CYP3A4ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463467-B1 Thermoplastic polycarbonate moulding compositions with flame retarding properties BAYER AG (DE) 1996-03-27 EP disclosed
EP-0463467-A2 Thermoplastic polycarbonate moulding compositions with flame retarding properties BAYER AG (DE) 1992-01-02 EP disclosed