Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432503 | 0.78 | KMT2A (0.59) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL27750481 | 0.73 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8957386 | 0.71 | MEN1 (0.70) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9152126 | 0.70 | KMT2A (0.56) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9475142 | 0.69 | KMT2A (0.59) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL11555074 | 0.68 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10877017 | 0.68 | NPC1 (0.53) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL9278712 | 0.68 | HPGD (0.64) | KMT2AMEN1CYP2C9ALOX15CYP2C19 | |
| SCHEMBL11556980 | 0.67 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28764104 | 0.67 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589490-A | BENZAMIDE DERIVATIVES WITH NITROXY ALKYL GROUPS | ITALFARMACO S.P.A. (IT) | 1996-12-31 | — | — | US | disclosed |
| EP-0540544-B1 | BENZOIC ACID SUBSTITUTED DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO SPA (IT) | 1995-02-15 | — | — | EP | disclosed |
| US-5366992-A | IN MIXTURE WITH AN EXCIPIENT | ITALFARMACO S.P.A. (IT) | 1994-11-22 | — | — | US | disclosed |
| WO-1992001668-A1 | BENZOIC ACID SUBSTITUTED DERIVATIVES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO S.P.A. (IT) | 1992-02-06 | — | — | WO | disclosed |