Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Roxatidine Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Roxatidine Acetate SCHEMBL29965995 | 0.98 | HRH2 (1.00) | HRH2HRH3 | |
| SCHEMBL11399763 | 0.98 | HRH2 (1.00) | HRH2HRH3 | |
| Roxatidine Acetate SCHEMBL1393 | 0.98 | HRH2 (1.00) | HRH2HRH3 | |
| Roxatidine Acetate SCHEMBL667643 | 0.97 | HRH2 (0.98) | HRH2HRH3 | |
| Roxatidine Acetate SCHEMBL29389759 | 0.97 | HRH2 (0.98) | HRH2HRH3 | |
| SCHEMBL11182082 | 0.97 | HRH2 (0.98) | HRH2HRH3 | |
| Roxatidine Acetate SCHEMBL1650455 | 0.96 | HRH2 (0.96) | HRH2HRH3 | |
| Roxatidine Acetate SCHEMBL2322201 | 0.94 | HRH2 (0.89) | HRH2HRH3 | |
| Roxatidine Acetate SCHEMBL482841 | 0.94 | HRH2 (0.93) | HRH2HRH3 | |
| SCHEMBL11179081 | 0.89 | HRH2 (0.83) | HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8333259-A | — | — | None | — | — | JP | disclosed |
| JP-H08333259-A | PHARMACEUTICAL PREPARATION COMPOSITION CONTAINING SUCRALFATE | CHUGAI PHARMACEUT CO LTD | 1996-12-17 | — | — | JP | disclosed |