Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806687 | 0.89 | FDPS (0.49) | FDPSANPEPERAP2PDE3ALMNA | |
| SCHEMBL9083416 | 0.84 | FDPS (0.43) | FDPSANPEPERAP2PDE3ALMNA | |
| SCHEMBL19193755 | 0.83 | FDPS (0.58) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL20572945 | 0.83 | FDPS (0.53) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL18962170 | 0.81 | FDPS (0.56) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL19193926 | 0.81 | FDPS (0.56) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL19193859 | 0.81 | FDPS (0.56) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8701605 | 0.79 | FDPS (0.51) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9081574 | 0.78 | ANPEP (0.40) | FDPSANPEPERAP2LMNASLC6A1 | |
| SCHEMBL9082307 | 0.78 | ANPEP (0.44) | FDPSANPEPERAP2PDE3ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519013-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | THE PROCTER & GAMBLE COMPANY (US) | 1996-05-21 | — | — | US | disclosed |
| US-5334586-A | Heterocycle-substituted diphosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | PROCTER & GAMPLE PHARMACEUTICALS, INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0586521-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021355-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| US-5071840-A | Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | disclosed |