Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | AGT | P01019 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.38 |
| ▸ | TLR2 | O60603 | 3/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413763 | 0.92 | AGTR1 (0.45) | AGTR1AGTR2AGTHDAC1HDAC6 | |
| SCHEMBL9488699 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2AGTHDAC1HDAC6 | |
| SCHEMBL2831925 | 0.83 | AGTR1 (0.46) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL2831924 | 0.83 | AGTR1 (0.46) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL3948155 | 0.82 | LTB4R2 (0.57) | AGTR1AGTR2AGTHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL2829155 | 0.82 | AGTR1 (0.45) | AGTR1AGTR2AGTPDCD1CD274 | |
| Hydrochloric Acid SCHEMBL2829151 | 0.82 | AGTR1 (0.45) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL9487777 | 0.82 | AGTR1 (0.44) | AGTR1AGTR2AGTPDCD1CD274 | |
| SCHEMBL9489945 | 0.82 | SIRT2 (0.47) | AGTR1AGTR2AGT | |
| SCHEMBL839981 | 0.81 | AGTR1 (0.47) | AGTR1AGTR2AGTPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530016-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |