Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 3/20 | 0.84 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9084684 | 1.00 | SLC6A1 (0.84) | SLC6A1CHRM5ADRA2ACYP2D6DRD2 | |
| Hydrochloric Acid SCHEMBL8859079 | 0.99 | SLC6A1 (0.82) | SLC6A1CHRM5ADRA2ACYP2D6DRD2 | |
| Hydrochloric Acid SCHEMBL8859074 | 0.99 | SLC6A1 (0.82) | SLC6A1CHRM5ADRA2ACYP2D6DRD2 | |
| SCHEMBL9084697 | 0.92 | SLC6A1 (1.00) | SLC6A1 | |
| SCHEMBL9084381 | 0.92 | SLC6A1 (1.00) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8859095 | 0.91 | SLC6A1 (0.98) | SLC6A1 | |
| Hydrochloric Acid SCHEMBL8859093 | 0.91 | SLC6A1 (0.98) | SLC6A1 | |
| SCHEMBL9083831 | 0.88 | SLC6A1 (0.81) | SLC6A1 | |
| SCHEMBL9086278 | 0.88 | SLC6A1 (0.64) | SLC6A1CHRM5ADRA2ACYP2D6DRD2 | |
| SCHEMBL9085197 | 0.88 | SLC6A1 (0.81) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735872-A1 | A METHOD OF TREATING NEUROGENIC INFLAMMATION | NOVO NORDISK A/S (DK) | 1996-10-09 | — | — | EP | claimed |
| EP-0585314-B1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK AS (DK) | 1996-09-18 | — | — | EP | claimed |
| WO-1995018615-A1 | A METHOD OF TREATING NEUROGENIC INFLAMMATION | NOVO NORDISK A/S (DK) | 1995-07-13 | — | — | WO | claimed |