Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252718 | 0.90 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL4914114 | 0.88 | CNR2 (0.66) | CNR1CNR2 | |
| SCHEMBL4904013 | 0.85 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL4902889 | 0.84 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL908612 | 0.84 | CNR2 (0.53) | CNR1CNR2 | |
| SCHEMBL908310 | 0.83 | CNR2 (0.75) | CNR1CNR2 | |
| SCHEMBL908827 | 0.83 | CNR2 (0.60) | CNR1CNR2 | |
| SCHEMBL4907403 | 0.81 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL2872140 | 0.81 | CNR2 (0.64) | CNR1CNR2 | |
| SCHEMBL8012882 | 0.80 | CNR2 (0.59) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875646-B2 | Cannabinoid receptor antagonist; N-{[5-(4-chlorophenyl)-4-cyano-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]methyl}-3-cyanobenzenesulfonamide; psychiatric disorder, substance dependence and withdrawal disorder, cognitive disorder, ADD, neurodegenerative diseases, pain, eating disorders, dyslipidemia, ulcer | SANOFI-AVENTIS (FR) | 2011-01-25 | — | — | US | disclosed |
| US-20080070962-A1 | DERIVATIVES OF N-[(1,5-DIPHENYL-1H-PYRAZOL-3-YL)METHYL] SULFONAMIDE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-03-20 | — | — | US | disclosed |
| US-7297710-B1 | Derivatives of N-[(1,5-diphenyl-1H-pyrazol-3-yl)methyl]sulfonamide, their preparation and their application in therapeutics | SANOFI-AVENTIS (FR) | 2007-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070962-A1 | DERIVATIVES OF N-[(1,5-DIPHENYL-1H-PYRAZOL-3-YL)METHYL] SULFONAMIDE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | PRMT5, PRMT3, PRMT1 | CNR1 93/4885CNR2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.