Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.70 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.70 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086870 | 0.88 | AGTR1 (0.72) | AGTR1AGTR2PPARG | |
| SCHEMBL13508735 | 0.88 | AGTR1 (0.72) | AGTR1AGTR2TLR7 | |
| SCHEMBL9129370 | 0.87 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL9086625 | 0.87 | AGTR1 (0.74) | AGTR1AGTR2PPARG | |
| SCHEMBL28487275 | 0.85 | AGTR1 (0.76) | AGTR1AGTR2PPARG | |
| SCHEMBL29411886 | 0.85 | AGTR1 (0.76) | AGTR1AGTR2PPARG | |
| SCHEMBL13508734 | 0.84 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL4952279 | 0.84 | AGTR1 (0.78) | AGTR1AGTR2PPARG | |
| SCHEMBL9122396 | 0.84 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL13261296 | 0.83 | AGTR1 (0.73) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519138-A | ANGIOTENSIN ANTAGONIST | DR. KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0529253-A1 | Phenylalkylderivatives, compounds containing them and process for their fabrication | Dr. Karl Thomae GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |