Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7739654 | 0.83 | POLB (0.47) | ACECA1CA2POLBGAA | |
| SCHEMBL7739653 | 0.83 | POLB (0.47) | ACECA1CA2POLBGAA | |
| SCHEMBL9088141 | 0.83 | HDAC1 (0.49) | CA1CA2POLBMAPTNPSR1 | |
| SCHEMBL9819558 | 0.80 | SYK (0.55) | MAPT | |
| SCHEMBL13570900 | 0.80 | SYK (0.55) | MAPT | |
| SCHEMBL13570899 | 0.80 | SYK (0.55) | MAPT | |
| SCHEMBL22612061 | 0.79 | MEN1 (0.48) | POLBGAAMAPTLTA4H | |
| SCHEMBL20630934 | 0.79 | MEN1 (0.48) | POLBGAAMAPTLTA4H | |
| SCHEMBL1376104 | 0.79 | MEN1 (0.48) | POLBGAAMAPTLTA4H | |
| SCHEMBL9088792 | 0.79 | P2RY12 (0.43) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506267-A | IMMUNOADJUVANT FOR BONE MARROW CELL GROWTH AFTERTREATMENT OF CHEMOTHERAPY OR RADIOTHERAPY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0641776-A2 | Thioglycerol derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |