Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24857179 | 0.84 | ALDH1A1 (0.45) | HPGDPDE4DKDM4ELMNAPKM | |
| SCHEMBL31572177 | 0.84 | ALDH1A1 (0.45) | HPGDPDE4DKDM4ELMNAPKM | |
| SCHEMBL2095153 | 0.81 | MAPT (0.40) | HPGDKDM4EPKMALDH1A1MAPT | |
| SCHEMBL18774743 | 0.78 | HPGD (0.55) | HPGDPDE4DSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2094993 | 0.77 | ALDH1A1 (0.48) | HPGDSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL9088755 | 0.77 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL30932668 | 0.77 | ALDH1A1 (0.48) | HPGDSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL10004608 | 0.77 | SMN1; SMN2 (0.47) | HPGDPDE4DKDM4ELMNAPKM | |
| SCHEMBL30873487 | 0.77 | MAPT (0.48) | HPGDPDE4DKDM4ELMNAPKM | |
| SCHEMBL26694663 | 0.77 | MAPT (0.48) | HPGDPDE4DKDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585491-A | Antibacterial agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0326891-B1 | Antibacterial agents | WARNER LAMBERT CO (US) | 1994-08-03 | — | — | EP | disclosed |
| EP-0398967-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4920120-A | 3-CARBOXY, 4-OXO, 6-FLUORO, 7-NITROGEN-CONTAINING RING 1,4-DIHYDRO-1,8-NAPHTHYRIDINES | WARNER-LAMBERT COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0326891-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989006649-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-07-27 | — | — | WO | disclosed |