Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9090733 | 0.94 | KMT2A (0.39) | KMT2A | |
| SCHEMBL9088617 | 0.91 | AGTR1 (0.42) | AGTAGTR1AGTR2 | |
| SCHEMBL9089573 | 0.87 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9088694 | 0.84 | KMT2A (0.41) | KMT2AAGTR1AGTR2 | |
| SCHEMBL9703945 | 0.84 | AGT (0.54) | AGTAGTR1AGTR2 | |
| SCHEMBL9088198 | 0.83 | KMT2A (0.46) | KMT2AAGTR2 | |
| SCHEMBL9090634 | 0.81 | KMT2A (0.43) | KMT2AAGTR1AGTR2 | |
| SCHEMBL9087950 | 0.80 | AGT (0.41) | AGTAGTR1AGTR2 | |
| SCHEMBL9088907 | 0.79 | AGTR1 (0.40) | AGTAGTR1AGTR2 | |
| SCHEMBL9088329 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519138-A | ANGIOTENSIN ANTAGONIST | DR. KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0529253-A1 | Phenylalkylderivatives, compounds containing them and process for their fabrication | Dr. Karl Thomae GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |