SCHEMBL9089974

SCHEMBL9089974

C=CC(=O)OCCCNC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.35
ACHE P22303 6/20 0.35
HCAR2 Q8TDS4 2/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
TGM2 P21980 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8910467 0.88 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16309324 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16384932 0.86 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9088962 0.85 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20382045 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2461678 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17225747 0.82 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23746700 0.81 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16806072 0.80 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL22217163 0.80 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9493670-B2 Coatings that provide hydrophilic surface EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-11-15 US claimed
EP-2999758-A1 PREPARATION OF PRESSURE SENSITIVE ADHESIVE DISPERSIONS FROM MULTI-STAGE EMULSION POLYMERIZATION FOR APPLICATIONS OF PROTECTIVE FILMS BASF SE (DE) 2016-03-30 EP claimed
US-20160075906-A1 COATINGS THAT PROVIDE HYDROPHILIC SURFACE CRESTLINE DIRECT FINANCE, L.P. 2016-03-17 US claimed
WO-2014171943-A1 COATINGS THAT PROVIDE HYDROPHILIC SURFACE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-10-23 WO claimed
EP-0358774-B1 NOVEL SPIROOXAZINE COMPOUNDS TORAY INDUSTRIES (JP) 1995-10-25 EP claimed
WO-2024130128-A1 CROSSLINKABLE COATING SYSTEM AND COATINGS PREPARED FROM THE SAME SWIMC LLC (US) 2024-06-20 WO disclosed
WO-2019159080-A1 IMPACT RESISTANT ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-22 WO disclosed
US-20180265712-A1 BINDER COMPOSITION FOR HEAT-SEALABLE FILM COATINGS BASF SE (DE) 2018-09-20 US disclosed
EP-3353245-A1 BINDER COMPOSITION FOR HEAT-SEALABLE FILM COATINGS BASF SE (DE) 2018-08-01 EP disclosed
CN-105408437-B Pressure-sensitive adhesive agent dispersion for protective film is prepared by multistage emulsion polymerization 巴斯夫欧洲公司 2018-05-18 CN disclosed
US-9815994-B2 Aqueous pigment dispersions with components to interact with cellulose E I DU PONT DE NEMOURS AND COMPANY (US) 2017-11-14 US disclosed
WO-2017050589-A1 BINDER COMPOSITION FOR HEAT-SEALABLE FILM COATINGS BASF SE (DE) 2017-03-30 WO disclosed
US-20160075906-A1 COATINGS THAT PROVIDE HYDROPHILIC SURFACE CRESTLINE DIRECT FINANCE, L.P. 2016-03-17 US disclosed
WO-2015038254-A2 AQUEOUS INKJET INKS CONTAINING POLYMERIC BINDERS WITH COMPONENTS TO INTERACT WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-03-19 WO disclosed
WO-2015020935-A2 AQUEOUS PIGMENT DISPERSIONS WITH COMPONENTS TO INTERACT WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-02-12 WO disclosed
WO-2014171943-A1 COATINGS THAT PROVIDE HYDROPHILIC SURFACE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-10-23 WO disclosed
US-5559231-A PHOTOCHROMIC, RECORDING MATERIAL, CLOTHING, GLASSES, WINDOWS TORAY INDUSTRIES, INC. (JP) 1996-09-24 US disclosed
EP-0358774-B1 NOVEL SPIROOXAZINE COMPOUNDS TORAY INDUSTRIES (JP) 1995-10-25 EP disclosed
US-5374723-A Photochromic dyes; resistance to repetition of coloration and discoloration TORAY INDUSTRIES, INC. (JP) 1994-12-20 US disclosed
EP-0358774-A1 NOVEL SPIROOXAZINE COMPOUNDS TORAY INDUSTRIES, INC. (JP) 1990-03-21 EP disclosed