SCHEMBL8910467

SCHEMBL8910467

C=CC(=O)OCCNC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.54
ALDH1A1 P00352 5/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HPGD P15428 1/20 0.48
THRB P10828 2/20 0.44
MAPK1 P28482 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.33
HCAR2 Q8TDS4 1/20 0.31
LMNA P02545 1/20 0.31
TGM2 P21980 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25823310 0.89 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9089974 0.88 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5663537 0.85 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12570601 0.83 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15639867 0.83 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1043171 0.83 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Benzene SCHEMBL28466958 0.82 THRB (0.49) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL701217 0.82 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17536060 0.82 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL13872046 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9464228-B2 Liquid crystal composition, method for manufacturing the same, and film FUJIFILM CORPORATION (JP) 2016-10-11 US claimed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US claimed
US-20150191652-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US claimed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US claimed
US-5597661-A Solid polymer electrolyte, battery and solid-state electric double layer capacitor using the same as well as processes for the manufacture thereof SHOWA DENKO K.K. (JP) 1997-01-28 US claimed
CN-114921129-B Self-repairing high-refractive-index ink and preparation method and application thereof 武汉工程大学 2023-09-19 CN disclosed
US-11732194-B2 Cholesteric liquid crystal layer, laminate, optically anisotropic body, reflective film, method for producing cholesteric liquid crystal layer, anti-counterfeit medium, and determination method FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
CN-115010849-B Solvent-free high-refractive-index optical material and preparation method and application thereof 武汉工程大学 2023-07-18 CN disclosed
US-11693278-B2 Liquid crystal diffraction element and method for producing liquid crystal diffraction element FUJIFILM CORPORATION (JP) 2023-07-04 US disclosed
US-20230161211-A1 METHOD FOR PRODUCING CHOLESTERIC LIQUID CRYSTAL LAYER, CHOLESTERIC LIQUID CRYSTAL LAYER, LIQUID CRYSTAL COMPOSITION, CURED PRODUCT, OPTICALLY ANISOTROPIC BODY, AND REFLECTIVE LAYER FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-11634638-B2 Liquid crystal composition, reflective layer, method for producing reflective layer, and copolymer FUJIFILM CORPORATION (JP) 2023-04-25 US disclosed
US-11579507-B2 Method for producing cholesteric liquid crystal layer, cholesteric liquid crystal layer, liquid crystal composition, cured product, optically anisotropic body, and reflective layer FUJIFILM CORPORATION (JP) 2023-02-14 US disclosed
EP-2105451-A2 Nitrile group-containing polymer and method of synthesizing the same, composition containing nitrile group-containing polymer, and laminate Fujifilm Corporation (JP) 2009-09-30 EP disclosed
EP-0555628-B1 Process for preparing isocyanates NIPPON CATALYTIC CHEM IND (JP) 1996-05-29 EP disclosed
EP-0658269-A1 SOLID POLYMER ELECTROLYTE, BATTERY AND SOLID-STATE ELECTRIC DOUBLE LAYER CAPACITOR USING THE SAME AS WELL AS PROCESSES FOR THE MANUFACTURE THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-06-21 EP disclosed
WO-1994029884-A2 SOLID POLYMER ELECTROLYTE, BATTERY AND SOLID-STATE ELECTRIC DOUBLE LAYER CAPACITOR USING THE SAME AS WELL AS PROCESSES FOR THE MANUFACTURE THEREOF SHOWA DENKO K.K. (JP) 1994-12-22 WO disclosed
US-5326903-A Thermal decomposition of carbamate NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0555628-A2 Process for preparing isocyanates NIPPON SHOKUBAI CO., LTD. (JP) 1993-08-18 EP disclosed
CN-85107374-B Process for producing water-absorbent resin SEITETSU KAGAKU CO.,LTD. (JP) 1987-08-26 CN disclosed
US-4383878-A RELEASE COATING OF RADIATION CURED POLYFLUORINATED ACRYLATE MONOMER, CURING AGENT AND POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM PYM1, C9, LANCL2 TSHR 4393/4885ALDH1A1 1441/4885TP53 3744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.