Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441621 | 0.91 | TSHR (0.49) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL8851962 | 0.88 | HSPA5 (0.51) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL76848 | 0.86 | HMGCR (0.47) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL30648250 | 0.83 | HSPA5 (0.67) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL3810039 | 0.83 | HSPA5 (0.67) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL9299589 | 0.80 | CYP3A4 (0.47) | HSPA5CYP2C19CYP2C9HIF1ACYP1A2 | |
| SCHEMBL8756022 | 0.79 | ALDH1A1 (0.46) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL29500375 | 0.78 | HSPA5 (0.66) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL39554 | 0.78 | HSPA5 (0.66) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL30903568 | 0.78 | HSPA5 (0.66) | HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500467-A | PHOSPHITES, DISCOLORATION INHIBITION | GENERAL ELECTRIC COMPANY (US) | 1996-03-19 | — | — | US | disclosed |