Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091441 | 0.83 | USP2 (0.34) | USP2TSHRSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9090872 | 0.81 | KMT2A (0.32) | USP2SMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL9282862 | 0.81 | NPC1 (0.33) | USP2TSHRSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9090532 | 0.77 | KMT2A (0.34) | USP2TSHRSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL8552583 | 0.73 | USP2 (0.33) | USP2TSHRSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL9090244 | 0.71 | HDAC6 (0.35) | TSHRKDM4E | |
| SCHEMBL8551474 | 0.71 | LTB4R (0.37) | USP2TSHRSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL8552582 | 0.71 | — | — | |
| SCHEMBL9091098 | 0.70 | KDM4E (0.50) | USP2TSHRSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL8603712 | 0.69 | NR1I2 (0.37) | USP2TSHRSMN1; SMN2NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |
| WO-1995031452-A1 | THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |