Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 6/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15877633 | 0.76 | GRM5 (0.53) | TNIKASIC3MAPTKDM4ECYP1A2 | |
| SCHEMBL11269556 | 0.71 | ASIC3 (0.44) | ASIC3L3MBTL1PGK1ALDH1A1KDM4E | |
| SCHEMBL487465 | 0.70 | MAPT (0.56) | TNIKASIC3MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL18561130 | 0.67 | MAPT (0.53) | ASIC3MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL16256042 | 0.67 | TTBK1 (0.36) | ASIC3L3MBTL1PGK1 | |
| SCHEMBL1201922 | 0.67 | GRM5 (0.49) | MAPTL3MBTL1ALDH1A1CYP1A2HPGD | |
| SCHEMBL12391039 | 0.66 | ASIC3 (0.50) | ASIC3MAPTL3MBTL1ALDH1A1MAP3K14 | |
| SCHEMBL4863464 | 0.65 | CYP2A6 (0.50) | CYP1A2 | |
| SCHEMBL737111 | 0.65 | CHAT (0.46) | ASIC3MAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL21751179 | 0.65 | ASIC3 (0.43) | TNIKASIC3L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583227-A | INHIBIT SECRETION OF GASTRIC ACID | MOCHIDA PHARMACEUTICAL CO. LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0685468-A1 | Pyrazine and quinoxaline derivatives and their use as anti-ulcer agents | Mochida Pharmaceutical Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |