Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | GOT1 | P17174 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615261 | 0.77 | RARA (0.42) | RARARARBRARGTDP1MEN1 | |
| SCHEMBL15765977 | 0.76 | CNR2 (0.48) | CNR2RARARARBRARGTDP1 | |
| SCHEMBL8615263 | 0.75 | RARA (0.39) | CNR2RARARARBRARGTDP1 | |
| SCHEMBL8434839 | 0.70 | RARA (0.41) | CNR2RARARARBRARGTDP1 | |
| SCHEMBL7929960 | 0.70 | RARA (0.44) | RARARARBRARGTDP1MEN1 | |
| SCHEMBL6429954 | 0.69 | RARA (0.57) | RARARARBRARGTDP1MEN1 | |
| SCHEMBL15766000 | 0.69 | TDP1 (0.51) | CNR2RARARARBRARGTDP1 | |
| SCHEMBL9091280 | 0.69 | EPHX2 (0.40) | RARARARBRARGTDP1MEN1 | |
| SCHEMBL8567722 | 0.69 | RARA (0.51) | CNR2RARARARBRARGTDP1 | |
| SCHEMBL8567726 | 0.69 | CNR2 (0.41) | CNR2RARARARBRARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574036-A | Adamantyl-substituted polycyclic acetylene compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1996-11-12 | — | — | US | claimed |