⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29152430 | 0.97 | — | — | |
| SCHEMBL1026265 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL28691668 | 0.77 | — | — | |
| Bromide SCHEMBL4821794 | 0.77 | — | — | |
| SCHEMBL1651954 | 0.77 | FDPS (0.45) | — | |
| SCHEMBL5713341 | 0.77 | DAO (0.50) | — | |
| Methylamine SCHEMBL27656294 | 0.76 | TSHR (0.42) | — | |
| SCHEMBL854767 | 0.75 | — | — | |
| SCHEMBL10680 | 0.74 | — | — | |
| SCHEMBL12181347 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213395-B | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114213395-A | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-03-22 | — | — | CN | claimed |
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | claimed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | claimed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| EP-2785697-B1 | N-(1H-PYRAZOLYL-METHYL) FORMAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS NITRIFICATION INHIBITORS | PIESTERITZ STICKSTOFF (DE) | 2016-02-03 | — | — | EP | claimed |
| EP-2785697-A1 | N-(1H-PYRAZOLYLMETHYL)FORMAMIDES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS NITRIFICATION INHIBITORS | SKW Stickstoffwerke Piesteritz GmbH (DE) | 2014-10-08 | — | — | EP | claimed |
| WO-2013079197-A1 | N-(1H-PYRAZOLYLMETHYL)FORMAMIDES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS NITRIFICATION INHIBITORS | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2013-06-06 | — | — | WO | claimed |
| US-8299072-B2 | Pyrazolylmethylamine compounds as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-30 | — | — | US | claimed |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-04-15 | — | — | US | claimed |
| EP-0765381-B1 | BLEACH ACTIVATION | UNILEVER NV (NL) | 1999-08-11 | — | — | EP | claimed |
| US-12358931-B2 | 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl) propanenitrile as a JAK kinase inhibitor | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2025-07-15 | — | — | US | disclosed |
| US-20240132520-A1 | NAPHTHYRIDINE COMPOUNDS AS JAK KINASE INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2024-04-25 | — | — | US | disclosed |
| US-11780852-B2 | Methods for treating Crohn's disease using 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-10-10 | — | — | US | disclosed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| WO-2001016268-A1 | METHOD OF PRETREATING AND BLEACHING STAINED FABRICS | UNILEVER PLC (GB) | 2001-03-08 | — | — | WO | disclosed |
| WO-2001016269-A1 | METHOD OF BLEACHING STAINED FABRICS | UNILEVER PLC (GB) | 2001-03-08 | — | — | WO | disclosed |
| CN-1073714-A | Detergent bleach compositions | UNILEVER NV (NL) | 1993-06-30 | — | — | CN | disclosed |
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |