Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.49 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266448 | 0.79 | AKR1C3 (0.36) | AKR1C3AKR1C2AKR1C1PTGS1WRN | |
| SCHEMBL1678767 | 0.79 | DAO (0.41) | DAOGSK3BAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27893992 | 0.78 | GABBR2 (0.47) | GABBR2GABBR1DAOGSK3BF2 | |
| SCHEMBL27680282 | 0.76 | GABBR2 (0.46) | GABBR2GABBR1DAOGSK3BF2 | |
| SCHEMBL27484445 | 0.76 | CYP2C9 (0.53) | GABBR2GABBR1DAOGSK3BF2 | |
| SCHEMBL27601947 | 0.75 | GABBR2 (0.37) | GABBR2GABBR1DAOKMT2AALDH1A1 | |
| SCHEMBL27572922 | 0.75 | GABBR2 (0.45) | GABBR2GABBR1DAOGSK3BF2 | |
| SCHEMBL23972469 | 0.73 | GABBR2 (0.50) | GABBR2GABBR1DAOGSK3BF2 | |
| SCHEMBL23258012 | 0.73 | GABBR2 (0.42) | GABBR2GABBR1DAOGSK3BF2 | |
| SCHEMBL5521104 | 0.73 | GABBR2 (0.46) | GABBR2GABBR1DAOGSK3BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935815-B2 | Imidazoyl pyridine compounds and salts thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20110009619-A1 | POLYCYCLIC COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009619-A1 | POLYCYCLIC COMPOUND | APP, BACE1, PSEN1 | GABBR2 2388/4885GABBR1 3054/4885DAO 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.