Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093636 | 0.79 | IDO1 (0.47) | IDO1LMNASIGMAR1 | |
| SCHEMBL31267512 | 0.76 | IDO1 (0.47) | IDO1LMNASIGMAR1DHFR | |
| SCHEMBL10044994 | 0.76 | IDO1 (0.55) | IDO1LMNASIGMAR1 | |
| SCHEMBL9092504 | 0.75 | IDO1 (0.46) | IDO1LMNASIGMAR1DHFR | |
| SCHEMBL6036848 | 0.74 | IDO1 (0.48) | IDO1LMNASIGMAR1 | |
| SCHEMBL28226710 | 0.74 | IDO1 (0.48) | IDO1LMNA | |
| SCHEMBL30593727 | 0.73 | IDO1 (0.52) | IDO1LMNASIGMAR1 | |
| SCHEMBL28105816 | 0.73 | IDO1 (0.52) | IDO1LMNASIGMAR1 | |
| SCHEMBL25190743 | 0.72 | IDO1 (0.55) | IDO1LMNASIGMAR1 | |
| SCHEMBL12530260 | 0.72 | IDO1 (0.55) | IDO1LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576453-A | Stable, sterically-protected, bonded phase silicas prepared from bifunctional silanes | ES INDUSTRIES (US) | 1996-11-19 | — | — | US | disclosed |