SCHEMBL6036848

SCHEMBL6036848

C[Si](C)(CCl)OCCCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.48
LMNA P02545 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
MAOA P21397 3/20 0.39
MAOB P27338 2/20 0.39
SIGMAR1 Q99720 2/20 0.38
FFAR1 O14842 1/20 0.38
NPC1 O15118 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8101238 0.89 SMN1; SMN2 (0.40) IDO1MEN1KMT2ANPC1RAB9A
SCHEMBL10044994 0.81 IDO1 (0.55) IDO1LMNAMEN1KMT2AL3MBTL1
SCHEMBL27878821 0.79 IDO1 (0.46) IDO1LMNAMEN1KMT2ASIGMAR1
SCHEMBL8100608 0.77 TSHR (0.44) IDO1LMNAL3MBTL1MAOBNPC1
SCHEMBL2252126 0.75 IDO1 (0.53) IDO1LMNAMEN1KMT2AL3MBTL1
SCHEMBL11275819 0.75 IDO1 (0.48) IDO1LMNAMEN1KMT2AL3MBTL1
SCHEMBL11241741 0.75 TDP1 (0.38) IDO1L3MBTL1SMN1; SMN2
SCHEMBL28105816 0.74 IDO1 (0.52) IDO1LMNAMEN1KMT2AL3MBTL1
SCHEMBL30593727 0.74 IDO1 (0.52) IDO1LMNAMEN1KMT2AL3MBTL1
SCHEMBL9092500 0.74 IDO1 (0.47) IDO1LMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6991852-B2 A silica-based material that includes a silica-based substrate and a polymerized organic material disposed thereon. The polymerized organic material is made from reactive organic moieties bonded to the silica-based substrate. REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-01-31 US disclosed
US-20040214381-A1 Process for the production of organic transistor and organic transistor PIONEER CORPORATION 2004-10-28 US disclosed
EP-1471586-A1 Process for the production of organic transistor and organic transistor Pioneer Corporation (JP) 2004-10-27 EP disclosed
US-20030219597-A1 Silica-based materials and methods REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2003-11-27 US disclosed
WO-2003078159-A1 SILICA-BASED MATERIALS AND METHODS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2003-09-25 WO disclosed