Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018973 | 0.82 | HDAC3 (0.73) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| SCHEMBL24035294 | 0.79 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| SCHEMBL3253491 | 0.75 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| SCHEMBL5068414 | 0.75 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| SCHEMBL20464042 | 0.74 | NPSR1 (0.41) | HDAC3HDAC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL12838390 | 0.74 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| SCHEMBL1455540 | 0.74 | ALDH1A1 (0.65) | HDAC3HDAC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL7421051 | 0.74 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| SCHEMBL2659566 | 0.73 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC6CDC7 | |
| Bromide SCHEMBL3958442 | 0.72 | HDAC3 (0.57) | HDAC3HDAC4HDAC1HDAC6CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004282-A1 | CARBAPENEM COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1996-02-15 | — | — | WO | disclosed |