Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092894 | 1.00 | TRPM8 (0.43) | TRPM8ALDH1A1LPAR1LPAR5 | |
| SCHEMBL9094572 | 0.92 | TRPM8 (0.43) | TRPM8ALDH1A1LPAR1LPAR5 | |
| SCHEMBL9094949 | 0.91 | LPAR1 (0.45) | LPAR1LPAR5 | |
| SCHEMBL9094945 | 0.91 | LPAR1 (0.45) | LPAR1LPAR5 | |
| SCHEMBL9096283 | 0.88 | LPAR1 (0.44) | LPAR1LPAR5 | |
| SCHEMBL9095468 | 0.88 | LPAR1 (0.44) | LPAR1LPAR5 | |
| SCHEMBL8493183 | 0.87 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL8494932 | 0.87 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL4959382 | 0.87 | LPAR1 (0.51) | LPAR1LPAR5 | |
| SCHEMBL4959388 | 0.87 | LPAR1 (0.51) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034850-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |