Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095163 | 0.97 | PPARG (0.65) | PPARGAGTR1AGTR2 | |
| SCHEMBL9095186 | 0.92 | AGTR1 (0.62) | PPARGAGTR1AGTR2 | |
| SCHEMBL9095305 | 0.91 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL8791375 | 0.90 | PPARG (0.53) | PPARGAGTR1AGTR2 | |
| SCHEMBL8788071 | 0.90 | AGTR1 (0.65) | PPARGAGTR1AGTR2 | |
| SCHEMBL9096407 | 0.88 | PPARG (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL8790175 | 0.87 | PPARG (0.52) | PPARGAGTR1AGTR2 | |
| SCHEMBL8788984 | 0.86 | PPARG (0.48) | PPARGAGTR1AGTR2 | |
| SCHEMBL9094249 | 0.86 | PPARG (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL8393674 | 0.85 | PPARG (0.81) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587393-A | ANGIOTENSIN ANTAGONIST USEFUL IN TREATING HYPERTENSION | DR. KARL THOMAE GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| US-5385925-A | Benzimidazoles, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1995-01-31 | — | — | US | disclosed |