Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20946377 | 0.82 | HTR6 (0.63) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31279869 | 0.82 | HDAC1 (0.66) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8932772 | 0.82 | HDAC1 (0.66) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4094100 | 0.82 | HTR6 (0.63) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19268814 | 0.82 | HTR6 (0.66) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4504878 | 0.82 | HTR6 (0.63) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3260344 | 0.81 | HTR6 (0.65) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29744143 | 0.81 | HTR6 (0.65) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28794515 | 0.80 | HDAC3 (0.67) | HTR6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13539228 | 0.80 | HDAC3 (0.52) | HTR6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571471-B1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5409941-A | 5-heteroyl indole derivatives | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0571471-A1 | 5-HETEROYL INDOLE DERIVATIVES. | PFIZER (US) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992013856-A1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |