Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095357 | 0.80 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL9096076 | 0.79 | HTR6 (0.53) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL724590 | 0.77 | HTR6 (0.71) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL4099158 | 0.76 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL29743955 | 0.74 | HTR6 (0.84) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL4941443 | 0.72 | HTR6 (0.80) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL2928254 | 0.71 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL725818 | 0.71 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL1996380 | 0.70 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL3331751 | 0.70 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571471-B1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5409941-A | 5-heteroyl indole derivatives | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0571471-A1 | 5-HETEROYL INDOLE DERIVATIVES. | PFIZER (US) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992013856-A1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |