Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095728 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDCYP3A4 | |
| SCHEMBL9095099 | 0.79 | HSD17B10 (0.33) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9095859 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL9095097 | 0.79 | HSD17B10 (0.33) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9093518 | 0.79 | DAO (0.43) | ALDH1A1KDM4EHSD17B10TSHRHPGD | |
| SCHEMBL9097057 | 0.79 | PDE4B (0.38) | ALDH1A1KDM4EHSD17B10HPGDCYP3A4 | |
| SCHEMBL24380300 | 0.78 | KDM4E (0.41) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9096295 | 0.78 | ALDH1A1 (0.54) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22408526 | 0.74 | KDM4E (0.45) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22185212 | 0.73 | CNR2 (0.48) | ALDH1A1KDM4EHSD17B10NQO2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |