Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096215 | 0.87 | DRD2 (0.57) | DRD2DRD4ALDH3A1ALDH1A1ADRA1D | |
| SCHEMBL9384529 | 0.80 | DRD2 (0.74) | DRD2DRD4ALDH3A1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL9094970 | 0.80 | DRD2 (0.48) | DRD2DRD4ALDH3A1ALDH1A1ADRA1D | |
| Hydrochloric Acid SCHEMBL9096836 | 0.79 | DRD2 (0.72) | DRD2DRD4ALDH3A1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL11149764 | 0.78 | DRD2 (0.58) | DRD2ALDH1A1ADRA1B | |
| SCHEMBL9096191 | 0.77 | DRD2 (0.62) | DRD2DRD4ALDH3A1ALDH1A1ALDH2 | |
| Hydrochloric Acid SCHEMBL9096185 | 0.76 | DRD2 (0.53) | DRD2DRD4ALDH3A1ALDH1A1ADRA1B | |
| Hydrochloric Acid SCHEMBL9097226 | 0.76 | DRD2 (0.52) | DRD2DRD4ALDH3A1ALDH1A1ADRA1D | |
| Hydrochloric Acid SCHEMBL9096767 | 0.76 | DRD2 (0.61) | DRD2DRD4ALDH3A1ALDH1A1ALDH2 | |
| SCHEMBL9095875 | 0.75 | DRD2 (0.83) | DRD2DRD4ALDH3A1ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |
| EP-0624156-A1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Astra Aktiebolag (SE) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993012085-A1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | AKTIEBOLAGET ASTRA (SE) | 1993-06-24 | — | — | WO | disclosed |