Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818771 | 0.90 | KDM4E (0.55) | LTA4HKDM4EPOLBEGFRESRRB | |
| SCHEMBL1152700 | 0.90 | KDM4E (0.55) | LTA4HKDM4EPOLBEGFRESRRB | |
| SCHEMBL10828015 | 0.89 | LTA4H (0.50) | LTA4HKDM4EPOLBMCHR1EGFR | |
| SCHEMBL11420440 | 0.87 | LTA4H (0.50) | LTA4HKDM4EPOLBMCHR1EGFR | |
| SCHEMBL5726548 | 0.86 | ESRRG (0.50) | LTA4HKDM4EPOLBEGFRESRRB | |
| SCHEMBL5728005 | 0.86 | ESRRG (0.50) | LTA4HKDM4EPOLBESRRBESR1 | |
| SCHEMBL9859794 | 0.85 | LTA4H (0.48) | LTA4HPOLBALOX5 | |
| SCHEMBL5725836 | 0.84 | HRH3 (0.48) | LTA4HKDM4EPOLBESRRGBCL2 | |
| SCHEMBL5726763 | 0.83 | KDM4E (0.46) | LTA4HKDM4EPOLBMCHR1ESRRB | |
| SCHEMBL5725326 | 0.83 | KDM4E (0.46) | LTA4HKDM4EPOLBMCHR1ESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491173-A | ESTROGENIC, ANTIESTROGENIC AGENTS, ANTITUMOR AGENTS | ORION-YHTYMA OY (FI) | 1996-02-13 | — | — | US | disclosed |