Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 16/20 | 0.47 |
| ▸ | CDK2 | P24941 | 16/20 | 0.47 |
| ▸ | CDK4 | P11802 | 9/20 | 0.47 |
| ▸ | CDK1 | P06493 | 7/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 15/20 | 0.45 |
| ▸ | CCND1 | P24385 | 8/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.45 |
| ▸ | CCND2 | P30279 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 3/20 | 0.39 |
| ▸ | TXK | P42681 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096131 | 0.80 | CCNE1 (0.61) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9048641 | 0.78 | CCNE1 (0.54) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9099254 | 0.76 | CCNE1 (0.51) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9049316 | 0.72 | CCNE1 (0.50) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9049051 | 0.72 | CCNE1 (0.48) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9096153 | 0.72 | ALPL (0.48) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9048380 | 0.71 | CCNE1 (0.56) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9426322 | 0.71 | CCNE1 (0.53) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL5216840 | 0.71 | CCNE1 (0.67) | CCNE1CDK2CDK4CDK1CCNE2 | |
| SCHEMBL9047074 | 0.71 | CCNE1 (0.47) | CCNE1CDK2CDK4CDK1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030370-A2 | THIAZOLE AND THIADIAZOLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS USEFUL IN THE TREATMENT OF THROMBOCYTOPENIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |