Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005973 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL6665516 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL2999647 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL15589454 | 0.94 | FKBP1A (0.49) | POLBFKBP1ANPSR1PREPNPC1 | |
| SCHEMBL19158857 | 0.94 | FKBP1A (0.49) | POLBFKBP1ANPSR1PREPNPC1 | |
| SCHEMBL13613076 | 0.92 | POLB (0.48) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL3541296 | 0.91 | POLB (0.48) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL15291850 | 0.91 | POLB (0.50) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL3541298 | 0.91 | POLB (0.48) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL28718975 | 0.91 | POLB (0.48) | POLBFKBP1ANPSR1PREPHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556981-A | Angiotensin II antagonist intermediates | ELI LILLY AND COMPANY (US) | 1996-09-17 | — | — | US | disclosed |